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Nature In Bottle certify that Saffron Oil is suitable for cosmetic application and is not included in the list of substances prohibited in cosmetic products. Neither does it contain parabens, restricted preservatives, colorants or UV filters (Annex II - VI of EU Regulation (EC) No 1223/2009). PubMed: A prospective double-blind randomized placebo-controlled study of the effect of saffron (Crocus sativus Linn.) on semen parameters and seminal plasma antioxidant capacity in infertile men with idiopathic oligoasthenoteratozoospermia. A number of studies have demonstrated that saffron has the potential to prevent and treat cancer. Research is at an early stage but the signs are good. According to the studies done so far, saffron and its major constituent – crocin may have an important role to play in the battle against various forms of cancer. PubMed: Improvement of cytotoxic and apoptogenic properties of crocin in cancer cell lines by its nanoliposomal form.
PubMed: Crocin suppresses tumor necrosis factor-alpha-induced cell death of neuronally differentiated PC-12 cells. PubMed: Protective effects of saffron (Crocus sativus) against lethal ventricular arrhythmias induced by heart reperfusion in rat: a potential anti-arrhythmic agent. PubMed: Cloning, structural characterization, and phylogenetic analysis of flower MADS-box genes from crocus (Crocus sativus L.). Be cautious if it’s your first time using saffron. It’s possible to develop an allergic reaction, so do a patch test first. Avoid saffron if you’re pregnant.PubMed: The expression of a chromoplast-specific lycopene beta cyclase gene is involved in the high production of saffron's apocarotenoid precursors. The reason for its high price is its labor-intensive harvesting method, which makes its production costly.
Erectile dysfunction (ED), the ability to maintain an erection, affects millions. And saffron could be a treatment for ED, according to some research. PubMed: Catalytic properties of three L-lactate dehydrogenases from saffron corms (Crocus sativus L). A 2010 study determined that this isn’t true. In the experiment, a lotion with saffron was applied to a group of people. Another group received lotion without saffron. Nature In Bottle does not conduct or commission animal testing of any cosmetic ingredient, raw material, or formulation of any finished product in the context of Cosmetics Regulation (EC) 1223/2009. Additionally, we do not buy any ingredient, formulation, or product from any supplier or manufacturer that conducted, commissioned, or had been a party to Animal Testing. We also encourages customers who manufacture cosmetics and skin care products to avoid animal-tested ingredients and offer cruelty-free products to their customers. Saffron has traditionally been used in parts of Asia to help manage anxiety and treat depression and research suggest that these traditional uses are valid.PubMed: Investigation of the neuroprotective action of saffron (Crocus sativus L.) in aluminum-exposed adult mice through behavioral and neurobiochemical assessment.
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